1. The transactions reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 13, 2020.

2. Represents part of a single option award grant, including Incentive Stock Options, initially for an aggregate 132,395 shares. 1/48th of the aggregate shares subject to the option became vested and exercisable on February 11, 2016 and 1/48th of the shares subject to the option become vested and exercisable on each monthly anniversary thereafter, such that all such shares subject to this award became fully vested on January 11, 2020.