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BAKER BROS. ADVISORS LP
Director, 10% Owner
BAKER BROS. ADVISORS LP
$17,265,048,000.00
%
COMPANY
SHARES
NET TOTAL
48.08%
Seagen Inc.
46,912,264
$8,300,656,000.00
15.91%
Incyte Corporation
36,154,116
$2,746,628,000.00
10.94%
BeiGene, Ltd.
11,668,897
$1,888,611,000.00
3.66%
BioMarin Pharmaceutical Inc.
7,620,494
$631,510,000.00
3.42%
ACADIA Pharmaceuticals Inc.
41,923,490
$590,702,000.00
2.61%
Ascendis Pharma A/S
4,852,655
$451,103,000.00
2.46%
argenx SE
1,119,557
$424,178,000.00
1.86%
Other
80,364,790
$321,751,000.00
0.78%
BioCryst Pharmaceuticals, Inc.
12,710,818
$134,480,000.00
0.77%
Kodiak Sciences Inc.
17,310,490
$132,252,000.00
0.69%
Global Blood Therapeutics, Inc.
3,732,502
$119,253,000.00
0.64%
AbCellera Biologics Inc.
10,450,180
$111,294,000.00
0.62%
Madrigal Pharmaceuticals, Inc.
1,499,213
$107,314,000.00
0.55%
Mirati Therapeutics, Inc.
1,409,784
$94,639,000.00
0.54%
Immunocore Holdings plc
2,520,730
$94,048,000.00
0.53%
Horizon Therapeutics Public Ltd Co
1,148,504
$91,605,000.00
0.49%
Cerus Corporation
16,067,558
$84,997,000.00
0.46%
Travere Therapeutics, Inc.
3,300,009
$79,959,000.00
0.36%
Replimune Group, Inc.
3,591,081
$62,772,000.00
0.33%
IGM Biosciences, Inc.
3,156,102
$56,905,000.00
0.33%
Kymera Therapeutics, Inc.
2,879,825
$56,704,000.00
0.31%
Krystal Biotech, Inc.
807,735
$53,036,000.00
0.31%
Prelude Therapeutics Inc.
10,123,824
$52,846,000.00
0.28%
Nurix Therapeutics, Inc.
3,882,125
$49,187,000.00
0.26%
Alkermes plc
1,500,000
$44,685,000.00
0.26%
ChemoCentryx, Inc.
1,792,657
$44,422,000.00
0.26%
Chinook Therapeutics, Inc.
2,534,102
$44,321,000.00
0.25%
Insmed Incorporated
2,156,001
$42,516,000.00
0.22%
Immatics N.V.
4,423,731
$38,531,000.00
0.22%
DBV Technologies S.A.
14,614,264
$37,266,000.00
0.18%
Amarin Corporation plc
21,169,804
$31,543,000.00
0.18%
Verastem, Inc.
26,988,898
$31,307,000.00
0.16%
Ultragenyx Pharmaceutical Inc.
470,974
$28,098,000.00
0.16%
Kiniksa Pharmaceuticals, Ltd.
2,799,577
$27,128,000.00
0.14%
Altimmune, Inc.
2,075,403
$24,282,000.00
0.14%
Invitae Corporation
9,873,488
$24,091,000.00
0.14%
Pacific Biosciences of California, Inc.
5,444,963
$24,067,000.00
0.13%
Xenon Pharmaceuticals Inc.
751,639
$22,865,000.00
0.13%
Heron Therapeutics, Inc.
8,131,678
$22,687,000.00
0.13%
Merus N.V.
995,397
$22,536,000.00
0.11%
Affimed N.V.
6,596,830
$18,273,000.00