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Palo Alto Investors LP
10% Owner
Palo Alto Investors LP
$1,132,649,000.00
%
COMPANY
SHARES
NET TOTAL
15.08%
BIOMARIN PHARMACEUTICAL INC
2,061,373
$170,826,000.00
13.21%
UNITED THERAPEUTICS CORP
634,806
$149,586,000.00
10.80%
ABIOMED INC
494,397
$122,368,000.00
10.17%
INSMED INC
5,840,398
$115,173,000.00
9.34%
AMICUS THERAPEUTICS INC
9,847,774
$105,765,000.00
6.93%
STAAR SURGICAL CO
1,106,567
$78,489,000.00
6.50%
BIOGEN INC
360,981
$73,618,000.00
5.37%
REVANCE THERAPEUTICS INC
4,405,039
$60,878,000.00
4.03%
PROTHENA CORP PLC
1,681,477
$45,652,000.00
2.43%
SAGE THERAPEUTICS INC
851,409
$27,501,000.00
2.40%
VANDA PHARMACEUTICALS INC
2,491,200
$27,154,000.00
2.24%
KARYOPHARM THERAPEUTICS INC
5,621,533
$25,353,000.00
2.09%
ACADIA PHARMACEUTICALS INC
1,678,196
$23,646,000.00
1.59%
ALKERMES PLC
603,400
$17,975,000.00
1.36%
EHEALTH INC
1,654,693
$15,438,000.00
1.04%
SYNDAX PHARMACEUTICALS INC
612,600
$11,786,000.00
0.93%
ALIGN TECHNOLOGY INC
44,305
$10,486,000.00
0.88%
EPIZYME INC
6,774,541
$9,959,000.00
0.77%
ANAPTYSBIO INC
431,024
$8,750,000.00
0.71%
CLOVIS ONCOLOGY INC
4,473,967
$8,053,000.00
0.50%
GRITSTONE ONCOLOGY INC
2,330,504
$5,640,000.00
0.48%
KEZAR LIFE SCIENCES INC
656,200
$5,427,000.00
0.39%
CYTOKINETICS INC
111,717
$4,389,000.00
0.36%
TRAVERE THERAPEUTICS INC
166,069
$4,024,000.00
0.11%
MIRUM PHARMACEUTICALS INC
64,700
$1,259,000.00
0.10%
ALIMERA SCIENCES INC
200,919
$1,099,000.00
0.06%
NOVAVAX INC
12,500
$643,000.00
0.06%
ALDEYRA THERAPEUTICS INC
160,800
$642,000.00
0.05%
MAGENTA THERAPEUTICS INC
432,300
$519,000.00
0.02%
UROGEN PHARMA LTD
24,500
$201,000.00
0.02%
TACTILE SYSTEMS TECHNOLOGY I
27,100
$198,000.00
0.01%
MARINUS PHARMACEUTICALS INC
31,330
$152,000.00